It is a well-known fact that India has the deepest and oldest traditions in the fields of linguistics, mathematics, logic, astronomy, medicine, and philosophy lies in its texts available in the form of Vedas and Upanishads, where we have lots of spirituality, along with a lot of philosophical curiosity about Brahma. Philosophy is a vision, which has many windows. A single logic can view cosmology, physics, psychology, and any field of life. The author has selected a window of physics and has evolved a new particle physics on the basis of Indian philosophy. The book introduces Indian philosophy in short and explained its interpretations in terms of particle physics. The author has explained the disintegrated 'existence (Karana Sarira)', which is the root cause of everything in this universe. On the basis of this research, the author has resolved 45 mysteries of modern science and proposes new thoughts to be considered by modern science.